ASAP6.1

ASAP4 variant with fast kinetics and the largest per-spike fluorescence increase among the ASAP sensor lineage.

Category: VSD-cpGFP GEVI · Published: 2024 · bioRxiv 2024

Speed: τ_on=3.99 ms, τ_off=4.89 ms

Dynamic Range: 204% ΔF/F per 100mV

Sensitivity: 50% ΔF/F per AP

Brightness: 1.412× vs asap4e

Research Papers (2)

Improving positively tuned voltage indicators for brightness and kinetics — Lee S, Zhang G, Gomez LC, Testa-Silva G, Hao YA, Hiramoto A, Jiang D, Roth RH, Ding JB, Clandinin TR, Roska B, Feldman D, Ji N, Lin MZ, bioRxiv 2024
Synaptic basis of feature selectivity in hippocampal neurons — Gonzalez KC, Negrean A, Liao Z, Terada S, Zhang G, Lee S, Ocsai K, Rozsa B, Lin MZ, Polleux F, Losonczy A, Nature 2024