2Photron
Chemigenetic voltage indicator built from Klebsormidium nitens rhodopsin and HaloTag, engineered for two-photon voltage imaging.
Category: Chemigenetic GEVI · Published: 2024 · bioRxiv 2024
Speed: τ_on=0.75 ms, τ_off=0.91 ms
Dynamic Range: -24% ΔF/F per 100mV
Sensitivity: 5.72% ΔF/F per AP
Brightness: 4.12× vs jedi2p
Research Papers (2)
- A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo — Villette V, et al., bioRxiv 2024
- Two-photon voltage imaging with rhodopsin-based sensors — Grimm C, et al., Neuron 2026