Ace2N-mNeon
First Opsin-fluorescent protein FRET voltage indicator using an Ace2 opsin,.
Category: eFRET GEVI · Published: 2015 · Science 2015
Speed: τ_on=0.36 ms, τ_off=0.42 ms
Dynamic Range: -17.9% ΔF/F per 100mV
Sensitivity: 5% ΔF/F per AP
Brightness: 4.51× vs EGFP
Research Papers (6)
- High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor — Gong Y, et al., Science 2015
- Long-term optical brain imaging in live adult fruit flies — Huang C, et al., Nature Communications 2018
- Comparative Evaluation of Genetically Encoded Voltage Indicators — Bando Y, et al., Cell Reports 2019
- Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators — Chamberland S, et al., eLife 2017
- Exploring Bioelectricity with Ace2N-mNeon during Zebrafish Embryogenesis — Wu Z, et al., bioRxiv 2024
- Imaging high-frequency voltage dynamics in multiple neuron classes of behaving mammals — Haziza S, et al., Cell 2025