PROPS
First microbial opsin-based voltage indicator, though only functional in bacteria and extremely dim.
Category: Opsin GEVI · Published: 2011 · Science 2011
Speed: τ_on=4.7 ms, τ_off=4.7 ms
Dynamic Range: 150% ΔF/F per 100mV
Research Papers (4)
- Electrical spiking in Escherichia coli probed with a fluorescent voltage-indicating protein — Kralj JM, Hochbaum DR, Douglass AD, Cohen AE, Science 2011
- Initial photophysical characterization of the proteorhodopsin optical proton sensor (PROPS) — Nadeau JL, Frontiers in Neuroscience 2015
- Voltage-gated calcium flux mediates Escherichia coli mechanosensation — Bruni GN, Weekley RA, Dodd BJT, Kralj JM, Proceedings of the National Academy of Sciences 2017
- Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides — Bruni GN, Kralj JM, eLife 2020