Bongwoori-R3

Bongwoori variant with an arginine-enriched linker that enlarges the fluorescence response and shifts voltage sensitivity near resting potential for robust action-potential imaging.

Category: VSD-single FP · Published: 2017 · Scientific Reports 2017

Speed: τ_on=11 ms, τ_off=10 ms

Dynamic Range: -20% ΔF/F per 100mV

Sensitivity: 5.9% ΔF/F per AP

Brightness: 1.89× vs bongwoori

Research Papers (4)

Improving a genetically encoded voltage indicator by modifying the cytoplasmic charge composition — Lee S, et al., Scientific Reports 2017
Engineering photoactivatability in genetically encoded voltage and pH indicators — Lee S, et al., Frontiers in Cellular Neuroscience 2019
Visualizing oscillations in brain slices with genetically encoded voltage indicators — Rhee JK, et al., Frontiers in Neuroanatomy 2021
Imaging electrical activity of retinal ganglion cells with fluorescent voltage and calcium indicator proteins in retinal degenerative rd1 blind mice — Jung Y, et al., ACS Chemical Neuroscience 2025