FlicR1
Red fluorescent GEVI using the same voltage-sensing domain as ArcLight.
Category: VSD-single FP · Published: 2016 · Journal of Neuroscience 2016
Speed: τ_on=3 ms, τ_off=2.8 ms
Dynamic Range: 6.6% ΔF/F per 100mV
Sensitivity: 2.6% ΔF/F per AP
Brightness: 1458× vs arch
Research Papers (5)
- A bright and fast red fluorescent protein voltage indicator that reports neuronal activity in organotypic brain slices — Abdelfattah AS, et al., Journal of Neuroscience 2016
- Fast, in vivo voltage imaging using a red fluorescent indicator — Kannan M, et al., Nature Methods 2018
- A high-speed, bright, red fluorescent voltage sensor to detect neural activity — Beck C, et al., Scientific Reports 2019
- In vitro testing of voltage indicators: Archon1, ArcLightD, ASAP1, ASAP2s, ASAP3b, Bongwoori-Pos6, BeRST1, FlicR1, and Chi-VSFP-Butterfly — Milosevic MM, et al., eNeuro 2020
- Screening and cellular characterization of genetically encoded voltage indicators based on near-infrared fluorescent proteins — Piatkevich KD, et al., ACS Chemical Neuroscience 2020