JEDI-1P
One-photon optimized GEVI evolved from ASAP2s with improved brightness, kinetics, and sensitivity.
Category: VSD-cpGFP GEVI · Published: 2023 · Nature Communications 2023
Speed: τ_on=0.54 ms, τ_off=1.2 ms
Dynamic Range: -56% ΔF/F per 100mV
Sensitivity: 31.2% ΔF/F per AP
Brightness: 2.44× vs asap3
Research Papers (6)
- Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy — Lu X, Wang Y, Liu Z, Gou Y, Jaeger D, St-Pierre F, Nature Communications 2023
- Cortex-wide voltage imaging in a sensory cued reaching task reveals fast subnetwork dynamics — Wang Y, Kim SH, He EJ, Le Chatelier B, Choi H, Jaeger D, bioRxiv 2025
- A fast and responsive voltage indicator with enhanced sensitivity for unitary synaptic events — Hao YA, Lee S, Roth RH, et al., Neuron 2024
- Absolute Membrane Potential Recording with ASAP-Type Genetically Encoded Voltage Indicators Using Fluorescence Lifetime Imaging — Nair AG, Rodewald M, Bae H, Rühl P, Popp J, Schmitt M, Meyer-Zedler T, Heinemann SH, ACS Chemical Neuroscience 2025
- An integrated platform for simultaneous wide-field voltage/calcium imaging and fMRI reveals neuronal infraslow dynamics underlying functional connectivity — Pan WJ, Daley L, Watters H, Meyer-Baese L, Gopinath K, Jaeger D, Keilholz S, bioRxiv 2026
- A photostable genetically encoded voltage indicator for imaging neural activities in tissue and live animals — Cao C, Zhu R, Zhou S, Zhao Z, Lin C, Liu S, Peng L, Subach FV, Piatkevich KD, Zou P, bioRxiv 2025