JEDI-3hyp

JEDI-2P variant with two-photon voltage sensitivity shifted toward hyperpolarized potentials for detecting subthreshold fluctuations below resting membrane potential.

Category: VSD-cpGFP GEVI · Published: 2026 · Nature Methods 2026

Speed: τ_on=0.48 ms, τ_off=2.11 ms

Dynamic Range: -51.5% ΔF/F per 100mV

Sensitivity: 36.4% ΔF/F per AP

Brightness: 0.86× vs jedi2p

Research Papers (1)

Designer indicators for two-photon recording of subthreshold voltage dynamics — Land MA, Galdamez M, Villette V, Zhu J, Lu X, Marosi M, et al., Nature Methods 2026