JEDI-3sub

JEDI-2P variant engineered for two-photon detection of subthreshold voltage fluctuations with enhanced responsiveness across the physiological voltage range.

Category: VSD-cpGFP GEVI · Published: 2026 · Nature Methods 2026

Speed: τ_on=0.63 ms, τ_off=2.23 ms

Dynamic Range: -63.5% ΔF/F per 100mV

Sensitivity: 42.8% ΔF/F per AP

Brightness: 0.96× vs jedi2p

Research Papers (1)

Designer indicators for two-photon recording of subthreshold voltage dynamics — Land MA, Galdamez M, Villette V, Zhu J, Lu X, Marosi M, et al., Nature Methods 2026