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Photoactivatable archaerhodopsin-derived indicator whose near-infrared fluorescence is reversibly enhanced by one-photon blue or two-photon near-infrared excitation, enabling optically sectioned voltage imaging in tissue.

Category: Opsin GEVI · Published: 2021 · Science Advances 2021

Speed: τ_on=1.2 ms, τ_off=2.7 ms

Dynamic Range: 41% ΔF/F per 100mV

Sensitivity: 28% ΔF/F per AP

Brightness: 3× vs archon1

Research Papers (1)

Photoactivated voltage imaging in tissue with an archaerhodopsin-derived reporter — Chien MP, Brinks D, Testa-Silva G, Tian H, Brooks FP III, Adam Y, Bloxham W, Gmeiner B, Kheifets S, Cohen AE, Science Advances 2021