paQuasAr3
Photoactivatable QuasAr3 variant that can be selectively activated.
Category: Opsin GEVI · Published: 2019 · Nature 2019
Speed: τ_on=0.8 ms, τ_off=0.69 ms
Dynamic Range: 40% ΔF/F per 100mV
Sensitivity: 23.5% ΔF/F per AP
Brightness: 2× vs quasar2
Research Papers (11)
- Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics — Adam Y, Kim JJ, Lou S, Zhao Y, Xie ME, Brinks D, Wu H, Mostajo-Radji MA, Kheifets S, Parot V, Chettih S, Williams KJ, Gmeiner B, Farhi SL, Madisen L, Buchanan EK, Kinsella I, Zhou D, Paninski L, Harvey CD, Zeng H, Arlotta P, Campbell RE, Cohen AE, Nature 2019
- All-optical electrophysiology reveals the role of lateral inhibition in sensory processing in cortical layer 1 — Fan LZ, et al., Cell 2020
- Scalable measurements of intrinsic excitability in human iPS cell-derived excitatory neurons using all-optical electrophysiology — Williams LA, et al., Neurochemical Research 2019
- Photoactivated voltage imaging in tissue with an archaerhodopsin-derived reporter — Chien MP, et al., Science Advances 2021
- High-fidelity estimates of spikes and subthreshold waveforms from 1-photon voltage imaging in vivo — Xie ME, et al., Cell Reports 2021
- Linearly polarized excitation enhances signals from fluorescent voltage indicators — Bloxham W, et al., Biophysical Journal 2021
- Video-based pooled screening yields improved far-red genetically encoded voltage indicators — Tian H, et al., Nature Methods 2023
- Statistically unbiased prediction enables accurate denoising of voltage imaging data — Eom M, et al., Nature Methods 2023
- Mechanism of sensory perception unveiled by simultaneous measurement of membrane voltage and intracellular calcium — Tokunaga T, et al., Communications Biology 2024
- Optical constraints on two-photon voltage imaging — Brooks FP III, et al., Neurophotonics 2024
- Robust self-supervised denoising of voltage imaging data using CellMincer — Wang B, et al., npj Imaging 2024