QuasAr6b

Archon1 variant evolved through video-based pooled screening with improved speed.

Category: Opsin GEVI · Published: 2023 · Nature Methods 2023

Speed: τ_on=0.8 ms, τ_off=0.8 ms

Dynamic Range: 24% ΔF/F per 100mV

Sensitivity: 27% ΔF/F per AP

Brightness: 2× vs archon1

Research Papers (2)

Video-based pooled screening yields improved far-red genetically encoded voltage indicators — Tian H, Davis HC, Wong-Campos JD, Park P, Fan LZ, Gmeiner B, Begum S, Werley CA, Borja GB, Upadhyay H, Shah H, Jacques J, Qi Y, Parot V, Deisseroth K, Cohen AE, Nature Methods 2023
All-optical electrophysiology reveals behavior-dependent dynamics of excitation and inhibition in the hippocampus — Yang Q, Baror-Sebban S, Kipper R, London M, Adam Y, Neuron 2026