Voltron2
Improved Voltron with enhanced sensitivity, retaining fast kinetics and photostability.
Category: Chemigenetic GEVI · Published: 2023 · Neuron 2023
Speed: τ_on=0.67 ms, τ_off=0.89 ms
Dynamic Range: -38% ΔF/F per 100mV
Sensitivity: 10.09% ΔF/F per AP
Brightness: 0.65× vs voltron
Research Papers (18)
- Photophysics-informed two-photon voltage imaging using FRET-opsin voltage indicators — Brooks FP, et al., Science Advances 2025
- Imaging neuronal voltage beyond the scattering limit — Chen TW, et al., Nature Methods 2025
- Large-scale deep tissue voltage imaging with targeted-illumination confocal microscopy — Xiao S, et al., Nature Methods 2024
- Two-photon voltage imaging with rhodopsin-based sensors — Grimm C, et al., Neuron 2026
- Orange/far-red hybrid voltage indicators with reduced phototoxicity enable reliable long-term imaging in neurons and cardiomyocytes — Liu Y, et al., PNAS 2023
- Miniaturized widefield microscope for high speed in vivo voltage imaging — Saladrigas CA, et al., Biomedical Optics Express 2025
- Relative phase of membrane potential theta oscillations between individual hippocampal neurons code space — Athif M, et al., bioRxiv 2025
- Dendritic excitations govern back-propagation via a spike-rate accelerometer — Park P, et al., Nature Communications 2025
- A fast and responsive voltage indicator with enhanced sensitivity for unitary synaptic events — Hao YA, et al., Neuron 2024
- Fast dendritic excitations primarily mediate back-propagation in CA1 pyramidal neurons during behavior — Lee BH, et al., bioRxiv 2026
- A dendrite-resolved, in vivo transfer function from spike patterns to dendritic Ca2+ — Wu X, et al., bioRxiv 2026
- A scalable, all-optical method for mapping synaptic connectivity with cell-type specificity — Moya MV, et al., bioRxiv 2025
- Voltage dynamics of dendritic integration and back-propagation in vivo — Wong-Campos JD, et al., bioRxiv 2023
- High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations — Weber TD, et al., Nature Neuroscience 2023
- Fast and light-efficient remote focusing for volumetric voltage imaging — Bohm UL, Judkewitz B, Nature Communications 2024
- All-optical reporting of inhibitory receptor driving force in the nervous system — Selfe JS, et al., Nature Communications 2024
- Synchronous ensembles of hippocampal CA1 pyramidal neurons during novel exploration — Chen EL, et al., eLife 2025
- A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo — Villette V, et al., bioRxiv 2024